Arsenal boss Arsene Wenger goes into his side's first game of the Champions League against Borussia Dortmund at the Signal Iduna Park with just three fit first choice defenders.
Calum Chambers is a doubt with tonsillitis, while left back Nacho Monreal and right back Mathieu Debuchy are already ruled out.
Kieran Gibbs will start in place of Debuchy.
Arsenal will be keen to start well with last year's second place finish in the group stage arguably costing them progression to the quarter finals, and having won in Dortmund last year, they will be confident of doing so.
Shinji Kagawa will play for Dortmund in his first European tie since switching from Manchester United, having starred in their 3-1 win over Freiburg.
Arsenal vs Borussia Dortmund is live on Sky Sports 5 from 7pm, kick off at 7.45pm.