Wayne Rooney will not be lining up against his former club as he prepares to sit down three league games as a result of the red card he picked up in the clash with West Ham United.
Paddy McNair will keep his spot in defence, as Phil Jones, Jonny Evans and Chris Smalling are also out.
For Everton, Steven Pienaar could be in contention, but Seamus Coleman and James McCarthy are doubts.
Manchester United vs Everton is live on BT Sport 1 from 11am. Kick off at 12pm
