The M25 has been reopened in both directions at junction 23 to 25 after this morning's fatal collision closed the carriageway for much of today (December 9).
The Highways Agency said a 40mph speed limit will be in place past the incident the scene for safety reasons.
A Peugeot car, a Scania lorry, a DAF artic lorry, a Mercedes lorry and a Romanian lorry were involved in the crash, which took place at around 1.50am when an HGV lorry crossed over the central barrier onto the opposite carriageway, colliding into other vehicles.
A Highways Agency spokesman said there will be a need to resurface the road this evening due to the damage to the carriageway.
She said: "There are severe delays in the area and drivers are strongly encouraged to allow extra time for their journey.
"There has also been another incident on the M25 anti-clockwise between junction 28 and 27. However, this has been cleared to the hard shoulder."
A 39-year-old man from Leicester died in the collision.